Somatic symptom disorder (SSD) is a condition in which a person has excessive thoughts and feelings relating to physical symptoms. SSD may cause anxiety and negative emotions. Read on to learn. Symptoms. Symptoms of somatic symptom disorder may be: Specific sensations, such as pain or shortness of breath, or more general symptoms, such as fatigue or weakness. Unrelated to any medical cause that can be identified, or related to a medical condition such as cancer or heart disease, but more significant than what's usually expected. Somatic mutations in GATA2 occur rarely in MPN and other myeloid neoplasms, 9,11-13 with the exception of MDS/AML associated with biallelic CEBPA mutations. 7 Our patient had a trinucleotide deletion c.1168_1170delAAG; p390delK, identical to that previously reported as a second somatic mutation in 2 other patients with coexisting germ line..

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